Biobanking / Biorepository

Biobanking resources at Duke include shared resources specializing in biological solid and liquid sample handling, external commercial biobanking services, referral to available biospecimen collections, and biobanking education for researchers. The Duke Biobank provides consultation in:

  • Biobank planning, operations and data management
  • Biobanking best practices
  • Sustainability and specimen use planning
  • Industry sponsored research utilizing biospecimens

Duke Biobank manages a searchable index of biospecimens that may be available for use. The Duke Biobank is leading the implementation of the institution-wide biospecimen information management system.

  • Index of Biospecimens is a catalog of existing clinical research biological samples at Duke that are available for research projects.
  • LabVantage® Biobanking Information Management System will serve as Duke’s biobanking information management system.

Biobanks at Duke

Biofluids Shared Resource — (BSR) The BSR (previously known as the DNA bank) holds approximately 500,000 human biological samples and offers biobanking services, including blood fractionation, DNA and RNA extraction, storage and tracking. Consider a meeting with the BSR Study Implementation Group to consult about how to best serve your biobanking needs.

Kathleen Price Bryan Brain Bank and Biorepository  — The Brain Bank provides Duke researchers and academic and industry collaborators access to a collection of over 1,000 frozen and formalin preserved brains, 400 cerebral spinal fluid biospecimens with accompanying clinical, pathology, and neurocognitive data, and over 6,200 DNA samples.

Duke Human Heart Repository (DHHR) — The DHHR has over 30,000  human heart samples from over 550 donors for research and is a resource for assay development, target identification, and sponsored research.

Biospecimen Repository and Processing Core — (BRPC) is Duke’s central tissue procurement core in the Department of Pathology and is supported by the Duke School of Medicine and the Duke Cancer Institute. BRPC provides services that include patient identification, informed consent, specimen collection, processing and annotation of specimens, storage and specimen distribution.

The MURDOCK Study — This community registry and biorepository in Kannapolis is a longitudinal community-based registry, managed by CTSI, that has banked more than 415,000 biospecimens (including plasma, serum, whole blood, PAXGene® RNA, buffy coat, and urine) from over 12,000 study participants who have contributed self-reported data during enrollment and follow-up timepoints.