Duke Clinical Research Institute (DCRI)

The Duke Clinical Research Institute (DCRI) is the world’s largest academic clinical research organization, whose mission is to develop, share, and implement knowledge that improves health around the world through innovative clinical research. The institute, which was officially founded in 1996, has helped to shape the fundamental approaches to clinical research and is known for conducting groundbreaking multi-national clinical trials, managing major national patient registries, and performing landmark outcomes research. With its roots in the Duke Databank for Cardiovascular Disease, the DCRI is a pioneer in cardiovascular and pediatric clinical research, and also encompasses multiple other therapeutic areas, including infectious disease, neuroscience, respiratory medicine, and nephrology.

With nearly 1,100 faculty and staff, the DCRI combines the clinical expertise and academic leadership of a premier teaching hospital with the full-service operational capabilities of a major contract research organization. The DCRI offers a full suite of clinical trial services as well as substantial resources dedicated to outcomes research and assessments and clinical database design and management.

The DCRI is dedicated to developing the next generation of clinical researchers as well as improving the practice of clinical research and care. The DCRI Fellowship Program, a unique two-year program that trains postdoctoral fellows and medical students in clinical research principles, has graduated over 300 fellows. Additionally, most Fridays the DCRI hosts the NIH Collaboratory Grand Rounds webinars, which discuss best practices for pragmatic clinical trials.