Translational Population Health Research

A full-service hub for translational population research.

The Translational Population Health Research (TransPop) group was founded in 2008 to develop a groundbreaking longitudinal community registry and biorepository (the MURDOCK Study) before becoming part of CTSI in 2017. The TransPop team leverages a unique combination of assets and tools to accelerate population health research, tailoring these capabilities to support the research needs of the Duke research community and collaborating research teams.

Current Collaborations

COPD Study
Collaboration with Boehringer Ingelheim on a 5-year observational study of Chronic Obstructive Pulmonary Disease

Project Baseline
Collaboration with Stanford University and Verily on a 4-year longitudinal cohort study

Metabolic Signatures Underlying Vascular Risk Factors for Alzheimertype Dementias
Funded by the NIH

Smokeless Tobacco Cessation
Funded by the NIH in partnership with the Duke School of Nursing

Diabetes Self-Management & Support LIVE Study
Funded by the NIH

Assessing the Quality of EHR Data and Participant-Reported Data
Funded by the Patient Centered Outcomes Research Institute

The MURDOCK Study 
More than 12,000 adults residing in a 20-zip code catchment area of Kannapolis/Cabarrus County, NC, ranging from 18 to 100+ years old. 

What diseases and health questions are researchers trying to improve with help from the MURDOCK Study and TransPop group?

How can we develop targeted approaches for preventing and treating prostate cancer, reduce disease disparities for African Americans, and improve outcomes for men of all races with aggressive disease?

What genetic markers contribute to severe acne and common treatment side effects, and how can we develop safer and more effective treatments?

What underlying risk factors contribute to Alzheimer’s development?

Can using an online virtual learning environment help people with Type II Diabetes learn how to manage their disease and control their blood sugar?

What biomarkers, or signals in the brain, can help doctors predict the onset and progression of MS?

How does aging contribute to changes in memory and thinking?

Can dietary supplements help correct problems in abnormal sperm function in men with certain genetic varients?

How do symptoms related to a history of smoking and lung disease progress over time in a community population?

What physical, environmental, and genetic factors contribute to the body’s changes over time?

For more information, go to 
Contact: or (704) 250-5861